13 hours ago 2

Giants at White Sox Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 27

It’s Friday, June 27, and the Giants (44-37) are in Chicago to take on the White Sox (26-55). Landen Roupp is slated to take the mound for San Francisco against Aaron Civale for Chicago.

The White Sox are coming off a 7-3 win over the Arizona Diamondbacks. That was just their third win in the last 10 games.

The Cubs also added a tick in the win column with a victory over the Cardinals. Shota Imanaga was solid in his return to the mound. He struck out three batters in five shutout innings, while only allowing one hit.

Let’s dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Giants at White Sox

Date: Friday, June 27, 2025
Time: 7:40PM EST
Site: Rate Field
City: Chicago, IL
Network/Streaming: Space City Home Network, Marquee Sports Network

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Giants at the White Sox

The latest odds as of Friday:

Moneyline: Giants (-168), White Sox (+141)
Spread: Giants -1.5
Total: 8.0 runs

Probable starting pitchers for Giants at White Sox

Pitching matchup for June 27, 2025: Landen Roupp vs. Aaron Civale
- Giants: Landen Roupp, (5-5, 3.67 ERA)
  Last outing (Seattle Mariners, 6/21): 4.2 Innings Pitched, 3 Earned Runs Allowed, 7 Hits Allowed, 2 Walks, and 2 Strikeouts
- White Sox: Aaron Civale, (1-4, 4.91 ERA)
  Last outing (Los Angeles Angels, 6/21): 6.0 Innings Pitched, 7 Earned Runs Allowed, 9 Hits Allowed, 1 Walks, and 6 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Giants at White Sox

The Giants have won 14 of their last 20 away games against teams with losing records
The Under has hit in each of the White Sox’s last 3 games with a rest advantage over their opponents
The Giants have failed to cover the Run Line in 9 of their last 11 games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Giants and the White Sox

Rotoworld Best Bet

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Giants and the White Sox:

Moneyline: NBC Sports Bet is recommending a play on the San Francisco Giants on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff: